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High-efficiency in-vitro detection system for the improvement of the diagnosis of COVID-19 disease

Researchers from the Health Research Institute of the Hospital Clínico San Carlos and the Universidad Politécnica de Madrid have developed a diagnostic system that will allow the detection of multiple and specific biomarkers of COVID-19 disease in a single biosensor, with promising results, using biod technology.

Since the global health crisis caused by the SARS-CoV-2 virus and COVID-19 disease began, the need for efficient, industrially scalable, and low-cost diagnostic techniques has become evident. Techniques that allow, not only for the detection of the disease, but also for having the ability to predict its severity and for becoming useful tools in the healthcare process .

Faced with this situation, the Center for Biomedical Technology and the Center for Biotechnology and Plant Genomics of the Universidad Politécnica Madrid, in conjunction with the Health Research Institute of the Hospital Clínico San Carlos , have developed this detection system for high-quality COVID-19 disease diagnostics, making use of biod technology .

It is an in-vitro diagnostic system for the detection of multiple markers on a single multiplexed sensor where patient serum is deposited. One of the advantages of this technology is that the required patient sample volume is very low; In the first tests carried out on serum, it has been shown that with only 3 microliters of patient sample and after the necessary incubation time, the reading system developed by biod can carry out the 16 measurements of the biosensor in just 5 min.

Successful tests have been carried out to recognize SARS-CoV-2-specific IgGs and IgMs, although other additional markers are being studied to assess the severity of the disease, in order to consider the possibility of including them in the diagnostic biosensors .

Review of the news on the UPM website: https://blogs.upm.es/covid19upm/2020/05/22/investigadores-del-clinico-y-de-la-upm-desarrollan-un-kit-para-la-mejora-del-diagnostico-de-covid-19/