Bio-optical detection was initially conceived by scientists from the research group of Optics, Photonics and Bio-Photonics within the Center of Biomedical Technology of the Universidad Politécnica de Madrid (UPM). From its founding in 2010 the company was focused primarily on R&D activities in collaboration with public and private institutions.
In 2017 biod was incorporated into BioHold with the explicit aim to expand its scope and commercialize services and products to the end-user market.

